Liberty Blue - Opcje

CEM Corporation

UV Monitoring Accessory
 
Take the guesswork out of peptide synthesis!

Maximize your peptide quality while increasing your synthesis efficiency!
The Liberty Blue system can be upgraded with the optional UV monitoring feature.  This system monitors the waste stream from the deprotection reactions and automatically modifies the synthesis conditions in difficult regions of the peptide.  The software features a user defined feedback loop that will allow for double coupling, extended coupling times, and capping to be used in any combination during the coupling of difficult amino acids of the peptide.  The UV monitoring feature provides many benefits including Information about coupling efficiency that can be used in subsequent syntheses, structural information about the peptide sequence, more efficient use of synthesis reagents, and improved peptide product. The UV monitor is incorporated directly into the unit requiring no additional bench space.
  • Field upgradable for existing customers
  • Features plug and play technology
  • Small and compact unit
  • Easy to use software interface
  • Generates detailed UV data
  • Makes synthesizing difficult peptides easier


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Figure 1


Resin Loading Accessory
 
CEM Liberty Blue
High Throughput Microwave Peptide Synthesis 
 
To increase the throughput of the Liberty Blue system an optional modular resin loading option is available that will allow up to 24 peptides to be synthesized sequentially. The resin loader comes in a 12 position module with an additional 12 position module that can be coupled to it. With the rapid 4 minutes cycle time along with the potential to synthesize 24 peptides unattended overnight, the Liberty Blue system provides throughput of peptides that is comparable to that of conventional high throughput systems but with considerably better purity.
 

 
Advantages of Fast Sequential Peptide Synthesis
  • Single Peptides Fast - 1 to 2 hours for standard length peptides
  • Less Complex Instrumentation - easier to maintain and operate
  • Eliminates Purification Bottleneck - purify peptides as soon as they are completed
  • Precise Control at each Step - unique methods can be run for each peptide
  • Higher Purity Peptides - reduces purification costs
 

 

Peptide Cleavage Option 
 
Isolate Peptides Cleanly and in a Fraction of the Time
 
The cleavage option is an isolated liquid handling module designed for performing the peptide cleavage step. The isolated module provides the advantage of protecting the Liberty Blue system from the harsh reagents required for the cleavage all while allowing the use of microwave irradiation to provide high quality peptides in excellent yields in a fraction of the time.
  • Full peptide cleavage in 30 minutes or less
  • Microcleavage in as little as 2 minutes
  • Improved peptide purity
  • Increased peptide yield